Molybdenum in PDB 1aa6: Reduced Form of Formate Dehydrogenase H From E. Coli

All present enzymatic activity of Reduced Form of Formate Dehydrogenase H From E. Coli:
1.2.1.2;

The structure of Reduced Form of Formate Dehydrogenase H From E. Coli, PDB code: 1aa6 was solved by P.D.Sun, J.C.Boyington, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 2.30
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	146.400, 146.400, 82.700, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 28.7

The structure of Reduced Form of Formate Dehydrogenase H From E. Coli also contains other interesting chemical elements:

Iron

(Fe)

4 atoms

The binding sites of Molybdenum atom in the Reduced Form of Formate Dehydrogenase H From E. Coli (pdb code 1aa6). This binding sites where shown within 5.0 Angstroms radius around Molybdenum atom.
In total only one binding site of Molybdenum was determined in the Reduced Form of Formate Dehydrogenase H From E. Coli, PDB code: 1aa6:

Molybdenum binding site 1 out of 1 in the Reduced Form of Formate Dehydrogenase H From E. Coli


Mono view


Stereo pair view

A full contact list of Molybdenum with other atoms in the Mo binding site number 1 of Reduced Form of Formate Dehydrogenase H From E. Coli within 5.0Å range: probe atom residue distance (Å) B Occ A:Mo803 b:28.7 occ:1.00 S12 A:MGD801 2.1 32.4 1.0 S13 A:MGD801 2.3 32.8 1.0 S13 A:MGD802 2.3 17.9 1.0 S12 A:MGD802 2.5 25.1 1.0 SE A:SEC140 2.5 20.0 1.0 C12 A:MGD801 3.1 38.4 1.0 C13 A:MGD801 3.2 39.8 1.0 C13 A:MGD802 3.4 19.1 1.0 C12 A:MGD802 3.4 20.8 1.0 CB A:SEC140 3.7 47.7 1.0 CA A:SEC140 3.7 47.8 1.0 OE1 A:GLN335 4.3 28.6 1.0 CA A:GLY334 4.3 17.5 1.0 O A:ALA137 4.5 39.2 0.5 NH2 A:ARG581 4.5 43.6 1.0 O A:ALA137 4.6 39.0 0.5 C11 A:MGD801 4.6 37.8 1.0 N A:GLN335 4.6 18.8 1.0 N A:SEC140 4.6 47.6 1.0 C14 A:MGD801 4.6 42.8 1.0 O A:HOH848 4.6 52.8 1.0 N A:GLY334 4.6 19.1 1.0 CD A:GLN335 4.8 27.7 1.0 C14 A:MGD802 4.8 18.6 1.0 C11 A:MGD802 4.8 23.6 1.0 N15 A:MGD801 4.9 47.2 1.0 C A:SEC140 4.9 48.8 1.0 C A:GLY334 4.9 17.4 1.0 CG A:GLN335 5.0 25.4 1.0 C10 A:MGD801 5.0 38.6 1.0

J.C.Boyington, V.N.Gladyshev, S.V.Khangulov, T.C.Stadtman, P.D.Sun. Crystal Structure of Formate Dehydrogenase H: Catalysis Involving Mo, Molybdopterin, Selenocysteine, and An FE4S4 Cluster. Science V. 275 1305 1997.
ISSN: ISSN 0036-8075
PubMed: 9036855
DOI: 10.1126/SCIENCE.275.5304.1305