Atomistry » Molybdenum » PDB 1n62-2c9x » 2a9c
Atomistry »
  Molybdenum »
    PDB 1n62-2c9x »
      2a9c »

Molybdenum in PDB 2a9c: Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site

Enzymatic activity of Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site

All present enzymatic activity of Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site:
1.8.3.1;

Protein crystallography data

The structure of Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site, PDB code: 2a9c was solved by E.Karakas, H.L.Wilson, T.N.Graf, S.Xiang, S.Jaramillo-Busquets, K.V.Rajagopalan, C.Kisker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.50
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 53.905, 122.572, 55.180, 90.00, 94.97, 90.00
R / Rfree (%) 15.6 / 23.7

Molybdenum Binding Sites:

The binding sites of Molybdenum atom in the Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site (pdb code 2a9c). This binding sites where shown within 5.0 Angstroms radius around Molybdenum atom.
In total 2 binding sites of Molybdenum where determined in the Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site, PDB code: 2a9c:
Jump to Molybdenum binding site number: 1; 2;

Molybdenum binding site 1 out of 2 in 2a9c

Go back to Molybdenum Binding Sites List in 2a9c
Molybdenum binding site 1 out of 2 in the Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site


Mono view


Stereo pair view

A full contact list of Molybdenum with other atoms in the Mo binding site number 1 of Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mo2501

b:14.9
occ:1.00
O A:HOH7504 1.7 14.4 1.0
O A:HOH7505 1.9 14.9 1.0
S1' A:MTE1501 2.3 13.8 1.0
SG A:CYS185 2.4 13.6 1.0
S2' A:MTE1501 2.5 13.1 1.0
C1' A:MTE1501 3.4 13.9 1.0
C2' A:MTE1501 3.4 13.6 1.0
CB A:CYS185 3.5 13.8 1.0
N A:ALA186 3.7 14.6 1.0
CA A:CYS185 3.7 14.0 1.0
N A:ALA297 4.1 14.5 1.0
OH A:TYR322 4.2 18.8 1.0
C A:CYS185 4.2 15.1 1.0
CG A:GLN138 4.2 19.3 1.0
NE2 A:GLN138 4.3 21.0 1.0
CZ A:TYR322 4.3 18.9 1.0
CB A:ALA297 4.4 13.1 1.0
CA A:ALA297 4.5 13.7 1.0
O A:HOH7537 4.5 15.4 1.0
CE1 A:TYR322 4.5 19.5 1.0
C A:GLY296 4.7 14.9 1.0
C6 A:MTE1501 4.7 13.6 1.0
CB A:ALA186 4.7 14.8 1.0
CA A:ALA186 4.8 14.4 1.0
C3' A:MTE1501 4.8 13.2 1.0
CD A:GLN138 4.8 20.4 1.0
CA A:GLY296 4.8 14.3 1.0
CB A:GLN138 5.0 19.1 1.0

Molybdenum binding site 2 out of 2 in 2a9c

Go back to Molybdenum Binding Sites List in 2a9c
Molybdenum binding site 2 out of 2 in the Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site


Mono view


Stereo pair view

A full contact list of Molybdenum with other atoms in the Mo binding site number 2 of Crystal Structure of R138Q Mutant of Recombinant Chicken Sulfite Oxidase with the Bound Product, Sulfate, at the Active Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mo5501

b:17.1
occ:1.00
O B:HOH9506 1.5 15.2 1.0
S2' B:MTE4501 2.3 13.0 1.0
SG B:CYS185 2.4 16.2 1.0
S1' B:MTE4501 2.5 12.8 1.0
C2' B:MTE4501 3.3 14.5 1.0
CB B:CYS185 3.4 15.5 1.0
C1' B:MTE4501 3.4 13.9 1.0
OH B:TYR322 3.5 20.2 1.0
CA B:CYS185 3.7 15.1 1.0
N B:ALA186 3.8 15.0 1.0
CZ B:TYR322 4.0 20.0 1.0
CG B:GLN138 4.1 20.2 1.0
CE1 B:TYR322 4.1 20.0 1.0
NE2 B:GLN138 4.1 21.3 1.0
N B:ALA297 4.2 14.5 1.0
C B:CYS185 4.2 15.0 1.0
O B:HOH9756 4.4 31.9 1.0
CB B:ALA297 4.5 14.0 1.0
CA B:ALA297 4.5 14.4 1.0
CD B:GLN138 4.7 21.1 1.0
C6 B:MTE4501 4.7 13.5 1.0
C B:GLY296 4.8 14.4 1.0
C3' B:MTE4501 4.8 14.2 1.0
CE2 B:TYR322 4.9 19.7 1.0
CB B:ALA186 4.9 14.6 1.0
CA B:ALA186 4.9 14.7 1.0
CB B:GLN138 4.9 19.6 1.0
CA B:GLY296 5.0 14.1 1.0

Reference:

E.Karakas, H.L.Wilson, T.N.Graf, S.Xiang, S.Jaramillo-Busquets, K.V.Rajagopalan, C.Kisker. Structural Insights Into Sulfite Oxidase Deficiency J.Biol.Chem. V. 280 33506 2005.
ISSN: ISSN 0021-9258
PubMed: 16048997
DOI: 10.1074/JBC.M505035200
Page generated: Tue Dec 15 05:16:52 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy