Molybdenum in PDB 7px0: Drosophila Melanogaster Aldehyde Oxidase 1

All present enzymatic activity of Drosophila Melanogaster Aldehyde Oxidase 1:
1.2.3.8;

The structure of Drosophila Melanogaster Aldehyde Oxidase 1, PDB code: 7px0 was solved by G.Vilela-Alves, C.Mota, M.J.Romao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.66 / 2.20
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	144.663, 127.914, 152.547, 90, 110.63, 90
R / Rfree (%)	17.5 / 22

The structure of Drosophila Melanogaster Aldehyde Oxidase 1 also contains other interesting chemical elements:

Iron

(Fe)

16 atoms

The binding sites of Molybdenum atom in the Drosophila Melanogaster Aldehyde Oxidase 1 (pdb code 7px0). This binding sites where shown within 5.0 Angstroms radius around Molybdenum atom.
In total 4 binding sites of Molybdenum where determined in the Drosophila Melanogaster Aldehyde Oxidase 1, PDB code: 7px0:
Jump to Molybdenum binding site number: 1; 2; 3; 4;

Molybdenum binding site 1 out of 4 in the Drosophila Melanogaster Aldehyde Oxidase 1


Mono view


Stereo pair view

A full contact list of Molybdenum with other atoms in the Mo binding site number 1 of Drosophila Melanogaster Aldehyde Oxidase 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mo1304 b:28.8 occ:0.53 MO A:MOS1304 0.0 28.8 0.5 O2 A:MOS1304 1.8 22.3 0.5 O1 A:MOS1304 1.9 23.8 0.5 S1' A:MTE1303 2.3 41.9 1.0 S A:MOS1304 2.4 27.2 0.5 S2' A:MTE1303 2.5 50.8 1.0 OE2 A:GLU1217 3.3 35.8 1.0 C1' A:MTE1303 3.3 43.2 1.0 C2' A:MTE1303 3.3 46.7 1.0 N A:GLY1045 4.0 32.9 1.0 CA A:GLY1044 4.0 29.4 1.0 N A:GLY781 4.2 18.6 1.0 CD A:GLU1217 4.2 33.0 1.0 C A:TYR780 4.3 19.3 1.0 O A:TYR780 4.3 20.6 1.0 CA A:GLY781 4.4 18.1 1.0 C A:GLY1044 4.6 32.4 1.0 C6 A:MTE1303 4.7 40.8 1.0 C3' A:MTE1303 4.7 46.8 1.0 CA A:ARG893 4.9 21.3 1.0 NE2 A:GLN749 4.9 16.4 1.0 CG A:GLU1217 4.9 30.0 1.0

Molybdenum binding site 2 out of 4 in the Drosophila Melanogaster Aldehyde Oxidase 1


Mono view


Stereo pair view

A full contact list of Molybdenum with other atoms in the Mo binding site number 2 of Drosophila Melanogaster Aldehyde Oxidase 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mo1304 b:40.1 occ:0.56 MO B:MOS1304 0.0 40.1 0.6 O2 B:MOS1304 1.9 33.7 0.6 O1 B:MOS1304 1.9 38.5 0.6 S1' B:MTE1303 2.3 56.0 1.0 S B:MOS1304 2.3 32.3 0.6 S2' B:MTE1303 2.6 52.7 1.0 C1' B:MTE1303 3.3 48.1 1.0 C2' B:MTE1303 3.4 49.2 1.0 OE2 B:GLU1217 3.4 44.0 1.0 N B:GLY781 4.1 17.3 1.0 N B:GLY1045 4.2 43.0 1.0 CA B:GLY781 4.2 17.6 1.0 CA B:GLY1044 4.2 35.7 1.0 C B:TYR780 4.3 18.1 1.0 CD B:GLU1217 4.4 36.4 1.0 O B:TYR780 4.5 17.1 1.0 NE2 B:GLN749 4.7 18.4 1.0 C6 B:MTE1303 4.7 44.6 1.0 C B:GLY1044 4.8 36.4 1.0 C3' B:MTE1303 4.8 47.9 1.0 CA B:ARG893 4.9 22.9 1.0 CA B:TYR780 5.0 18.9 1.0 CG B:GLU1217 5.0 31.0 1.0 N B:ARG893 5.0 24.3 1.0

Molybdenum binding site 3 out of 4 in the Drosophila Melanogaster Aldehyde Oxidase 1


Mono view


Stereo pair view

A full contact list of Molybdenum with other atoms in the Mo binding site number 3 of Drosophila Melanogaster Aldehyde Oxidase 1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mo1304 b:38.8 occ:0.58 MO C:MOS1304 0.0 38.8 0.6 O1 C:MOS1304 1.9 31.2 0.6 O2 C:MOS1304 1.9 34.3 0.6 S1' C:MTE1303 2.3 52.0 1.0 S C:MOS1304 2.4 31.4 0.6 S2' C:MTE1303 2.6 58.6 1.0 C1' C:MTE1303 3.3 50.2 1.0 OE2 C:GLU1217 3.3 35.4 1.0 C2' C:MTE1303 3.3 52.0 1.0 N C:GLY1045 4.1 38.1 1.0 N C:GLY781 4.2 21.9 1.0 CA C:GLY1044 4.2 37.7 1.0 CD C:GLU1217 4.3 35.8 1.0 CA C:GLY781 4.3 21.4 1.0 C C:TYR780 4.4 22.9 1.0 O C:TYR780 4.6 23.0 1.0 C C:GLY1044 4.7 41.3 1.0 NE2 C:GLN749 4.7 22.1 1.0 C6 C:MTE1303 4.7 47.4 1.0 C3' C:MTE1303 4.8 53.7 1.0 CA C:ARG893 4.9 25.9 1.0 CG C:GLU1217 5.0 32.5 1.0

Molybdenum binding site 4 out of 4 in the Drosophila Melanogaster Aldehyde Oxidase 1


Mono view


Stereo pair view

A full contact list of Molybdenum with other atoms in the Mo binding site number 4 of Drosophila Melanogaster Aldehyde Oxidase 1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mo1304 b:39.0 occ:0.56 MO D:MOS1304 0.0 39.0 0.6 O1 D:MOS1304 1.8 32.5 0.6 O2 D:MOS1304 1.9 38.8 0.6 S1' D:MTE1303 2.3 44.9 1.0 S D:MOS1304 2.4 33.1 0.6 S2' D:MTE1303 2.5 66.8 1.0 C1' D:MTE1303 3.3 49.3 1.0 C2' D:MTE1303 3.4 48.3 1.0 OE2 D:GLU1217 3.6 37.8 1.0 N D:GLY1045 3.9 43.9 1.0 CA D:GLY1044 3.9 37.8 1.0 N D:GLY781 4.1 21.8 1.0 CA D:GLY781 4.2 20.8 1.0 C D:TYR780 4.3 24.5 1.0 C D:GLY1044 4.5 43.5 1.0 O D:TYR780 4.5 22.4 1.0 CD D:GLU1217 4.5 37.9 1.0 NE2 D:GLN749 4.5 25.1 1.0 C6 D:MTE1303 4.7 47.7 1.0 C3' D:MTE1303 4.8 47.5 1.0 CA D:ARG893 5.0 23.2 1.0 CA D:TYR780 5.0 24.3 1.0

G.Vilela-Alves, C.Mota, M.J.Romao. Drosophila Melanogaster'S Aldehyde Oxidase 1: the First Invertebrate Aox Structure To Be Published.